Colloidal drug delivery systems present a range of therapeutic benefits in the treatment of a number of challenging conditions, allowing researchers to cross barriers that have previously prevented efficient treatment while offering improved and more targeted absorption. Summarizing recent research in the field, Colloids in Drug Delivery assembles the work of 65 of the world’s leading colloid scientists who examine the full spectrum of this rapidly emerging science, from pure to applied, most of it drawn from their own experience and research.
The book begins by examining the basics of surfactant and polymer surface activity and self-assembly, the various types of structures formed by such compounds, and their use in drug delivery and biotechnology. It examines the development of controlled and targeted delivery systems by utilizing the various properties of colloids before moving on to discuss various applications and fields of research.
Topics discussed include:
- The use of hard, soft, and macromolecular colloidal drug delivery systems formed by surfactants, polymers, proteins, and lipids
- Recent advances in procolloidal systems, self-emulsifying drug delivery systems, and aerosol applications to pharmaceutical drug delivery
- Colloidal nanocarriers for imaging applications and the treatment of dental and periodontal diseases
- Classification and application of colloidal drug delivery systems in tumor targeting
- The use of colloids for improved nasal, ocular, vaginal, oral, buccal, gastrointestinal, and colon drug delivery
Examining topics necessary to the critical evaluation of a drug candidate’s potential for delivery, the book also describes the preparation, classification, interfacial activity, surface modifications and influence on particle characteristics, drug delivery, and drug targeting. Each chapter in this expansive volume explains why a particular system is used for the intended application, how it is made, and how it behaves.
All those concerned with the research, development, and manufacture of drugs will find this a valuable reference, offering a wealth of research upon which they can build.
Table of Contents
Surfactants and Block Copolymers in Drug Delivery; A. Misra, K. Florence, M. Lalan, and T. Shah
Application of Colloidal Properties in Drug Delivery; S. Saraf
Polymeric Nanocapsules for Drug Delivery: An Overview; S. S. Guterres, F. S. Poletto, L. M. Colomé, R. P. Raffin, and A. R. Pohlmann
Poly(Alkyl Cyanoacrylate) Nanoparticles for Drug Delivery and Vaccine Development; A. Graf, K. Krauel-Göllner, and T. Rades
Stimuli-Sensitive Polymer Gels for Dermal and Transdermal Drug Delivery and Their Application in the Development of Smart Textile Materials; W. Musial and V. Kokol
Micelles: The Multifunctional Nanocarrier for Colloidal Drug Delivery; C. Mohanty, S. Acharya, and S. K. Sahoo
Multiple Emulsions: An Overview and Pharmaceutical Applications; J. Khurana, S. Singh, and A. K. Dash
Pharmaceutical and Biotechnological Applications of Multiple Emulsions; R. Cortesi and E. Esposito
Nanoemulsions as Drug Delivery Systems; F. Tirnaksiz, S. Akkus, and N. Celebi
Microemulsion Systems: Application in Delivery of Poorly Soluble Drugs; L. Djekic and M. Primorac
Diclofenac Solubilization in Mixed Nonionic Surfactants Microemulsions; M. Fanun
Self-Emulsifying Drug Delivery Systems; D. P. Maurya, Y. Sultana, and M. Abul Kalam
Liquid Crystals and Their Application in the Field of Drug Delivery; R. Patel and T. N. Patel
Liquid Crystalline Nanoparticles as Drug Nanocarriers; A. Yaghmur and M. Rappolt
Niosomal Delivery System for Macromolecular Drugs; Y. Huang, F. Yu, and W. Liang
A New Class of Mesoscopic Aggregates as a Novel Drug Delivery System; F. Bordi, C. Cametti, and S. Sennato
Liposomes and Biomacromolecules: Effects of Preparation Protocol on In Vitro Activity; P. Luciani, D. Berti, and P. Baglioni
Colloidal Nanocarrier Systems as a Tool for Improving Antimycobacterial and Antitumor Activities and Reducing the Toxicity of Usnic Acid; N. S. Santos-Magalhães, N. P. S. Santos, M. C. B. Lira, M. S. Ferraz, E. C. Pereira and N. H. Silva
Dendrimers in Drug Delivery; H. Yang
Microsphere: A Novel Drug Delivery System; A. Samad, M. Tariq, M. I. Alam, and M. S. Akhter
Colloids in Aerosol Drug Delivery Systems; N. Islam
Respiratory Aerosol Dynamics with Applications to Pharmaceutical Drug Delivery; J. Xi, P. Worth Longest, and P. J. Anderson
Colloidal Carriers for Drug Delivery in Dental Tissue Engineering; N. Kalaji, N. Sheibat-Othman, and H. Fessi
Classification and Application of Colloidal Drug Delivery Systems: Passive or Active Tumor Targeting; H. Yesim Karasulu, B. Karaca, and E. Karasulu
Nanocarriers for Imaging Applications; V. Patravale and M. Joshi
Monzer Fanun is a member of the faculty of Science and Technology at Al-Quds University.